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Article

A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis.

BMC medical genetics - 20 Mar 2013

Greliche Nicolas, Germain Marine, Lambert Jean-Charles, Cohen William, Bertrand Marion, Dupuis Anne-Marie, Letenneur Luc, Lathrop Mark, Amouyel Philippe, Morange Pierre-Emmanuel, Trégouët David-Alexandre

Abstract excerpt

BACKGROUND: Venous Thrombosis (VT) is a common multifactorial disease with an estimated heritability between 35% and 60%. Known genetic polymorphisms identified so far only explain ~5% of the genetic variance of the disease. This study was aimed to investigate whether pair-wise interactions between common single nucleotide polymorphisms (SNPs) could exist and modulate the risk of VT. METHODS: A genome-wide SNP x...

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Identifiers

PMID: 23509962
DOI: 10.1186/1471-2350-14-36
PMCID: PMC3607886

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IRX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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