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Article

Random biopsies in patients harboring a CDH1 mutation: time to change the approach?

Revista espanola de enfermedades digestivas - 1 May 2020

Castro Rui, Lobo João, Pita Inês, Videira Flávio, Pedro-Afonso Luís, Dinis-Ribeiro Mário, Brandão Catarina

Abstract excerpt

INTRODUCTION AND AIM: hereditary diffuse gastric cancer (HDGC) can be caused by a CDH1 mutation. It often presents as multiple foci of signet ring cell carcinoma (SRCC) that is rarely detected by gastroscopy. Prophylactic total gastrectomy is recommended at a young age. The aim of this study was to determine the adequacy of gastroscopy according to the Cambridge protocol in patients with a CDH1 mutation. METHODS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32338015
DOI: 10.17235/reed.2020.6720/2019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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