Article
Prospective cohort study assessing outcomes of patients from families fulfilling criteria for hereditary diffuse gastric cancer undergoing endoscopic surveillance.
Gastrointestinal endoscopy - 1 Jul 2014
Lim Yean Cheant, di Pietro Massimiliano, O'Donovan Maria, Richardson Susan, Debiram Irene, Dwerryhouse Susan, Hardwick Richard H, Tischkowitz Marc, Caldas Carlos, Ragunath Krish, Fitzgerald Rebecca C
Abstract excerpt
BACKGROUND: Prophylactic total gastrectomy is performed in hereditary diffuse gastric cancer (HDGC) patients carrying the CDH1 mutation because endoscopic surveillance often fails to detect microscopic disease. OBJECTIVE: The aim of this study was to determine the natural history and outcomes of patients with HDGC undergoing endoscopy. DESIGN: Prospective, cohort observational study. SETTINGS: Tertiary referral...
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