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Gastroscopic surveillance with targeted biopsies compared with random biopsies in CDH1 mutation carriers

14 May 2020

Abstract excerpt

Abstract Background The International Gastric Cancer Linkage Consortium (IGCLC) consensus guideline advises prophylactic gastrectomy in early adulthood to prevent gastric cancer development in CDH1 germline mutation carriers; psychosocial reasons may postpone gastrectomy. We analyzed the yield of signet-ring cell carcinoma (SRCC) during surveillance gastroscopy in CDH1 mutation carriers. Methods A retrospective...

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PMID: 32408363
DOI: 10.1055/a-1157-8678

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