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Article

Causal relationships between blood lipids and depression phenotypes: a Mendelian randomisation analysis.

Psychological medicine - 1 Oct 2021

So Hon-Cheong, Chau Carlos Kwan-Long, Cheng Yu-Ying, Sham Pak C

Abstract excerpt

BACKGROUND: The etiology of depression remains poorly understood. Changes in blood lipid levels were reported to be associated with depression and suicide, however study findings were mixed. METHODS: We performed a two-sample Mendelian randomisation (MR) analysis to investigate the causal relationship between blood lipids and depression phenotypes, based on large-scale GWAS summary statistics (N = 188 577/480 359...

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Identifiers

PMID: 32329708
DOI: 10.1017/S0033291720000951

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