Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR-654-5p and miR-450b-5p.

doi:10.1111/cas.14429

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Article

Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR-654-5p and miR-450b-5p.

Cancer science - 1 Jul 2020

Zhang Jiakang, Furuta Takuya, Sabit Hemragul, Tamai Sho, Jiapaer Shabierjiang, Dong Yu, Kinoshita Masashi, Uchida Yasuo, Ohtsuki Sumio, Terasaki Tetsuya, Zhao Shiguang, Nakada Mitsutoshi

Abstract excerpt

We have previously shown that gelsolin (GSN) levels are significantly lower in the blood of patients with glioblastoma (GBM) than in healthy controls. Here, we analyzed the function of GSN in GBM and examined its clinical significance. Furthermore, microRNAs involved in GSN expression were also identified. The expression of GSN was determined using western blot analysis and found to be significantly lower in GBM...

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PMID: 32324311
DOI: 10.1111/cas.14429
PMCID: PMC7385387

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.