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Article

Large-scale analysis reveals the specific clinical and immune features of B7-H3 in glioma

23 Aug 2018

Abstract excerpt

Background: B7-H3 is an immune checkpoint member that belongs to B7-CD28 families and plays a vital role in the inhibition of T-cell function. Importantly, B7-H3 is widely overexpressed on solid tumors, making it become an attractive target for cancer immunotherapy. To clarify the expression panel of B7-H3 in glioma, we explored the clinical and immune features of B7-H3 expression in a large-scale study. Methods...

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PMID: 30377558
DOI: 10.1080/2162402x.2018.1461304

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