Article
Human leukocyte antigen G single-nucleotide polymorphism -201 (CC-CC) donor-recipient genotype matching as a predictor of severe cardiac allograft vasculopathy.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Sept 2016
Lazarte Julieta, Goldraich Livia, Manlhiot Cedric, Billia Filio, Ross Heather, Rao Vivek, Delgado Diego
Abstract excerpt
BACKGROUND: In heart transplant recipients, human leukocyte antigen G (HLA-G) has been shown to inhibit endothelial and smooth muscle cells injury in vitro, suggesting protection against cardiac allograft vasculopathy (CAV). Although the expression of HLA-G is regulated by single-nucleotide polymorphisms (SNPs), their association with CAV remains unknown. Therefore, the objective of this study was to determine...
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