Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intergenerational Effects of Maternal Holocaust Exposure on FKBP5 Methylation

21 Apr 2020

Abstract excerpt

Objective: There is growing evidence that exposure to trauma prior to conception can affect offspring. The authors have reported that adult offspring of Holocaust survivors showed lower methylation of FK506 binding protein 5 (FKBP5) intron 7, site 6 compared with Jewish comparison volunteers. The present study sought to replicate this finding in a larger sample and to examine parental and offspring correlates of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent and Pediatric Healthcare
Share to Child Abuse and Trauma
Share to Maternal Mental Health During Pregnancy and Postpartum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32312110
DOI: 10.1176/appi.ajp.2019.19060618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intergenerational Effects of Maternal Holocaust Exposure on FKBP5 MethylationPMID 32312110Read ↗

Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions.Semantic proximity Read ↗

No association between FKBP5 gene methylation and acute and long-term cortisol output.Semantic proximity Read ↗

Intergenerational gene × environment interaction of FKBP5 and childhood maltreatment on hair steroids.Semantic proximity Read ↗

Change in FK506 binding protein 5 (FKBP5) methylation over time among preschoolers with adversity.Semantic proximity Read ↗

Maternal posttraumatic stress and FKBP5 Genotype interact to predict trauma-related symptoms in preschool-age offspring.Semantic proximity Read ↗

The FKBP5 genotype and childhood trauma effects on FKBP5 DNA methylation in patients with psychosis, their unaffected siblings, and healthy controls.Semantic proximity Read ↗

The rs1360780 Variant of FKBP5: Genetic Variation, Epigenetic Regulation, and Behavioral PhenotypesSemantic proximity Read ↗

FKBP5 polymorphisms modify the effects of childhood trauma.Semantic proximity Read ↗

Placental FKBP5 genetic and epigenetic variation is associated with infant neurobehavioral outcomes in the RICHS cohort.Semantic proximity Read ↗

Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency.Semantic proximity Read ↗

Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders.Semantic proximity Read ↗

Maternal Exposure to the Holocaust and Health Complaints in OffspringSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.