Article
BaGPipe: an automated, reproducible, and flexible pipeline for bacterial genome-wide association studies.
BMC microbiology - 27 Mar 2026
Wei Kuangyi Charles, Blane Beth, Toussaint Jacqueline, Reuter Sandra, Toleman Michelle S, Torok Mili Estee, Peacock Sharon J, Harrison Ewan M, Aggarwal Dinesh, Roberts-Sengier William
Abstract excerpt
BACKGROUND: Microbial genome-wide association studies (GWAS) are crucial for linking genetic variation to phenotypic traits in bacteria. However, current tools often involve complex manual processing, limited scalability, and fragmented workflows, which constrain large-scale or routine bacterial GWAS. RESULTS: We developed BaGPipe, an automated and flexible bacterial GWAS pipeline built using Nextflow and...
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