Article
Improving cord blood typing with next-generation sequencing: impact of allele-level HLA and NIMA determination on their selection for transplantation.
Bone marrow transplantation - 1 Aug 2020
Enrich Emma, Vidal Francisco, Corrales Irene, Campos Eva, Borràs Nina, Martorell Lluís, Sánchez Mar, Querol Sergi, Rudilla Francesc
Abstract excerpt
Allele-level HLA compatibility in cord blood transplantation, together with noninherited maternal antigen or NIMA matching, have been associated with better transplant outcomes. The aim of this work is to develop a cost-efficient high-resolution HLA typing strategy based on next-generation sequencing to improve the quality of the Barcelona Cord Blood Bank's inventory, and to investigate the impact of...
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