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Potential Protective Role of SDF-1 and CXCR4 Gene Variants in the Development of Dementia.

Psychiatria Danubina - 1 Jan 2020

Dalan Burak, Timirci-Kahraman Ozlem, Gulec-Yilmaz Seda, Altinkilic Emre Murat, Duman Selvi, Ayhan Huseyin, Isbir Turgay

Abstract excerpt

BACKGROUND: The aim of this study was to evaluate the role of polymorphisms of stromal cell-derived factor-1 (SDF-1) and chemokine receptor-4 (CXCR4) genes in dementia susceptibility in a Turkish population. SUBJECTS AND METHODS: The study group included 61 dementia patients, while the control group comprised 82 healthy individuals. Gene polymorphisms of SDF-1 3'A G801A (rs1801157) and CXCR4 C138T (rs2228014)...

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PMID: 32303038
DOI: 10.24869/psyd.2020.92

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