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Article

Down-regulated lncRNA SBF2-AS1 in M2 macrophage-derived exosomes elevates miR-122-5p to restrict XIAP, thereby limiting pancreatic cancer development.

Journal of cellular and molecular medicine - 1 May 2020

Yin Zi, Zhou Yu, Ma Tingting, Chen Sheng, Shi Ning, Zou Yiping, Hou Baohua, Zhang Chuanzhao

Abstract excerpt

Evidence has indicated that M2 macrophages promote the progression of cancers, but few focus on the ability of M2 macrophage-derived exosomes in pancreatic cancer (PC). This study aims to explore how M2 macrophages affect malignant phenotypes of PC through regulating long non-coding RNA SET-binding factor 2 antisense RNA 1 (lncRNA SBF2-AS1)/microRNA-122-5p (miR-122-5p)/X-linked inhibitor of apoptosis protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32301277
DOI: 10.1111/jcmm.15125
PMCID: PMC7205800

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