Article

Hepatic stellate cell-derived exosome miR-122-5p targets TNFRSF19 to inhibit EMT and fibrosis in intrahepatic biliary epithelial cells via the p38 MAPK pathway

2023-06-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background and aim</bold>: Primary biliary cholangitis (PBC) is a kind of autoimmune mediated chronic cholestatic liver disease, Intrahepatic biliary epithelial cells (IBECs) are the main target cells. The precise effect of miR-122-5p, especially exosomal miR-122-5p in PBC has not been elucidated. <bold>Methods</bold>: RNA-sequence analyzed the expression profiles of ncRNAs in per...

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Literature Corpus work: 50c77dcb-7c65-55e5-9e66-574550bccacf
DOI: 10.21203/rs.3.rs-2997966/v1

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