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Article

CYP Genotypes Are Associated with Toxicity and Survival in Osteosarcoma Patients.

Journal of adolescent and young adult oncology - 1 Dec 2020

Trujillo-Paolillo Alini, Salinas-Souza Carolina, Dias-Oliveira Indhira, Petrilli Antônio S, Toledo Sílvia R C

Abstract excerpt

Purpose: Osteosarcoma is the malignant bone tumor most common in children and adolescents. Many cytochrome P-450 (CYP) members detoxify anticancer drugs used in osteosarcoma treatment, and thus, the aim of the present study was to investigate CYP polymorphisms in osteosarcoma patients. Methods: The present study investigated DNA from peripheral blood from 70 osteosarcoma patients treated with high doses of...

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Identifiers

PMID: 32298597
DOI: 10.1089/jayao.2019.0180

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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