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Article

Glutathione S-transferase polymorphisms in osteosarcoma patients.

Pharmacogenetics and genomics - 1 Aug 2010

Salinas-Souza Carolina, Petrilli Antonio S, de Toledo Silvia R C

Abstract excerpt

BACKGROUND: Osteosarcoma is the most common malignant bone tumor in children and adolescents. Multidrug resistance and poor clinical outcome are the problems that still affect osteosarcoma patients. The glutathione S-transferase supergene family includes several genes that encode enzymes involved in the detoxification of many xenobiotic agents, including carcinogens and anticancer drugs. The polymorphisms in...

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Source

Identifiers

PMID: 20577141
DOI: 10.1097/FPC.0b013e32833caa45

Genes

GSTM1
GSTM3
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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