Article
The pharmacogenomics of osteosarcoma.
The pharmacogenomics journal - 1 Jan 2017
Serra M, Hattinger C M
Abstract excerpt
Osteosarcoma (OS), the most common malignant tumor of bone, is presently treated with multidrug neoadjuvant chemotherapy protocols, which allow to cure 60-65% of patients but also induce toxicity events that cannot be predicted or efficiently prevented. The identification and validation of pharmacogenomic biomarkers is, therefore, absolutely warranted to provide the bases for planning personalized treatments with...
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