Article
Retrospective analysis of the association of the expression and single nucleotide polymorphisms (SNPs) of the TLR4, PTX3 and Dectin-1 (CLEC/A) genes with development of invasive aspergillosis among haematopoietic stem cell transplant recipients with oncohaematological disorders.
Mycoses - 1 Aug 2020
Kalkanci Ayse, Tug Esra, Fidan Isil, Guzel Tunccan Ozlem, Ozkurt Zubeyde Nur, Yegin Zeynep Arzu, Sahin Elif Ayça, Kuralay Zeynep
Abstract excerpt
OBJECTIVES: Several studies described single nucleotide polymorphisms (SNPs) on pattern recognition receptor (PRR) such as toll-like receptors (TLRs), dendritic cell-associated C-type lectin-1 (Dectin-1/CLEC7A) genes of patients with invasive fungal infections (IFIs) caused by Candida and Aspergillus. We screened TLR4, Dectin-1 and PTX3 polymorphisms in a Turkish population with invasive aspergillosis (IA)...
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