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Article

Genetic variants of dectin-1 and their antifungal immunity impact in hematologic malignancies: A comprehensive systematic review.

Current research in translational medicine - 1 Dec 2024

Aghaei Mojtaba, Khademi Reyhane, Far Mohammad Ali Jalali, Bahreiny Seyed Sobhan, Mahdizade Amir Hossein, Amirrajab Nasrin

Abstract excerpt

BACKGROUND: Fungal infections pose a significant threat to individuals with hematologic malignancies due to compromised immune systems. Dectin-1, a pivotal pattern recognition receptor, plays a central role in antifungal immune responses. Understanding its genetic variants' impact is crucial for advancing personalized therapeutic approaches. METHODS: Employing systematic review methods, studies were meticulously...

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Identifiers

PMID: 39038414
DOI: 10.1016/j.retram.2024.103460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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