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Article

Regulation of polycystin expression, maturation and trafficking.

Cellular signalling - 1 Aug 2020

Hu Jinghua, Harris Peter C

Abstract excerpt

The major autosomal dominant polycystic kidney disease (ADPKD) genes, PKD1 and PKD2, are wildly expressed at the organ and tissue level. PKD1 encodes polycystin 1 (PC1), a large membrane associated receptor-like protein that can complex with the PKD2 product, PC2. Various cellular locations have been described for both PC1, including the plasma membrane and extracellular vesicles, and PC2, especially the...

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Identifiers

PMID: 32275942
DOI: 10.1016/j.cellsig.2020.109630
PMCID: PMC7269868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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