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Oxidant/Antioxidant Profile in the Thoracic Aneurysm of Patients with the Loeys-Dietz Syndrome.

Oxidative medicine and cellular longevity - 1 Jan 2020

Soto Maria Elena, Manzano-Pech Lináloe G, Guarner-Lans Verónica, Díaz-Galindo Jorge A, Vásquez Xicoténcatl, Castrejón-Tellez Vicente, Gamboa Ricardo, Huesca Claudia, Fuentevilla-Alvárez Giovanny, Pérez-Torres Israel

Abstract excerpt

Patients with the Loeys-Dietz syndrome (LDS) have mutations in the TGF-βR1, TGF-βR2, and SMAD3 genes. However, little is known about the redox homeostasis in the thoracic aortic aneurysms (TAA) they develop. Here, we evaluate the oxidant/antioxidant profile in the TAA tissue from LDS patients and compare it with that in nondamaged aortic tissue from control (C) subjects. We evaluate the enzymatic activities of...

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Identifiers

PMID: 32273946
DOI: 10.1155/2020/5392454
PMCID: PMC7128053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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