Article
Novel aspects of oxidative stress in cardiovascular diseases.
Circulation journal : official journal of the Japanese Circulation Society - 1 Feb 2009
Heistad Donald D, Wakisaka Yoshinobu, Miller Jordan, Chu Yi, Pena-Silva Ricardo
Abstract excerpt
Oxygen radicals, and other reactive oxygen species, may play an important role in the pathophysiology of atherosclerosis, stroke, and other cardiovascular diseases. Mechanisms that account for oxidative stress in different cardiovascular diseases are diverse; for example, increases in activity of NAD(P)H oxidase, "uncoupling" of nitric oxide synthase, and maladaptive changes in expression of antioxidants can all...
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