Article
Loci associated with genomic damage levels in chronic kidney disease patients and controls.
Mutation research. Genetic toxicology and environmental mutagenesis - 1 Apr 2020
Corredor Zuray, da Silva Filho Miguel Inácio, Rodríguez-Ribera Lara, Catalano Calogerina, Hemminki Kari, Coll Elisabeth, Silva Irene, Diaz Juan Manuel, Ballarin José Aurelio, Henández Alba, Försti Asta, Marcos Ricard, Pastor Susana
Abstract excerpt
Chronic kidney disease (CKD) is a multifactorial disorder with an important genetic component, and several studies have demonstrated potential associations with allelic variants. In addition, CKD patients are also characterized by high levels of genomic damage. Nevertheless, no studies have established relationships between DNA damage, or genomic instability present in CKD patients, and gene polymorphisms. To...
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