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Article

DNA Damage in Chronic Kidney Disease: Evaluation of Clinical Biomarkers

1 Jan 2016

Abstract excerpt

Patients with chronic kidney disease (CKD) exhibit an increased cancer risk compared to a healthy control population. To be able to estimate the cancer risk of the patients and to assess the impact of interventional therapies thereon, it is of particular interest to measure the patients' burden of genomic damage. Chromosomal abnormalities, reduced DNA repair, and DNA lesions were found indeed in cells of patients...

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Identifiers

PMID: 27313827
DOI: 10.1155/2016/3592042

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