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Article

Roles of DNA damage in renal tubular epithelial cells injury

6 Apr 2023

Abstract excerpt

The prevalence of renal diseases including acute kidney injury (AKI) and chronic kidney disease (CKD) is increasing worldwide. However, the pathogenesis of most renal diseases is still unclear and effective treatments are still lacking. DNA damage and the related DNA damage response (DDR) have been confirmed as common pathogenesis of acute kidney injury and chronic kidney disease. Reactive oxygen species (ROS)...

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PMID: 37089416
DOI: 10.3389/fphys.2023.1162546

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