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Article

Exploring the therapeutic potential of interleukin-6 receptor blockade in cardiovascular disease treatment through Mendelian randomization.

Scientific reports - 13 Sept 2024

Ou Guangyang, Cai Huzhi, Yao Kunpeng, Qiu Zerui, Yang Yang, Chen Yaowu, Chen Xinyu

Abstract excerpt

Interleukin-6 (IL-6) plays a crucial role in the pathogenesis of cardiovascular disease (CVD), and IL-6 receptor (IL-6R) blockade has emerged as a promising therapeutic option. However, their specific therapeutic effects in different types of CVDs remain unclear. This study aimed to assess the efficacy of IL-6R blockade in the management of various CVDs, including hypertension (HTN), coronary heart disease (CHD),...

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Source

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Identifiers

PMID: 39271913
DOI: 10.1038/s41598-024-72195-4
PMCID: PMC11399143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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