Article
Gene polymorphisms of uric acid are associated with pre-eclampsia in South Africans of African ancestry.
Hypertension in pregnancy - 1 May 2020
Khaliq Olive P, Konoshita Tadashi, Moodely Jagidesa, Ramsuran Veron, Naicker Thajasvarie
Abstract excerpt
Objectives: To investigate the association of uric acid gene polymorphisms and Pre-eclampsia.Methods: 637 women of African ancestry [280 controls, 357 pre-eclampsia (early-onset = 187, late-onset = 170]) retrospectively. The rs505802, rs1212986, and rs1014290 SNPs were genotyped from purified DNA using real-time PCR.Results: CT genotype (rs505802) was higher in pre-eclampsia [Adjusted p = 0.028*: OR (95%...
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