Article
APOL1 genotype associated risk for preeclampsia in African populations: Rationale and protocol design for studies in women of African ancestry in resource limited settings.
PloS one - 1 Jan 2022
Osafo Charlotte, Thomford Nicholas Ekow, Coleman Jerry, Carboo Abraham, Guure Chris, Okyere Perditer, Adu Dwomoa, Adanu Richard, Parekh Rulan S, Burke David
Abstract excerpt
BACKGROUND: Women of African ancestry are highly predisposed to preeclampsia which continues to be a major cause of maternal death in Africa. Common variants in the APOL1 gene are potent risk factor for a spectrum of kidney disease. Recent studies have shown that APOL1 risk variants contribute to the risk of preeclampsia. The aim of the study is to understand the contribution of APOL1 risk variants to the...
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