Article
SLC17A7 gene may be the indicator of selective serotonin reuptake inhibitor treatment response in the Chinese Han population.
Journal of clinical psychopharmacology - 1 Jun 2014
Li Xin, Yu Tao, Huang Xiaoye, Cao Yanfei, Li Xingwang, Liu Baocheng, Yang Fengping, Li Weidong, Zhao Xinzhi, Feng Guoyin, Zhang Xu, Dong Zaiquan, Lin Yi, Li Xirong, He Lin, Sun Xueli, He Guang
Abstract excerpt
Selective serotonin reuptake inhibitors (SSRIs) are widely used drugs for major depressive disorder (MDD), although the treatment outcomes vary in different people. The vesicular glutamate transporter 1 coded by SLC17A7 gene has been reported associated with MDD. According to its role in glutamate transmission, it is reasonable to consider it as a potential pharmacogenetic candidate in SSRI treatment. A total of...
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