Article
Frequency of mutations associated with resistance to first- and second-line drugs in multidrug-resistant Mycobacterium tuberculosis isolates.
Journal of global antimicrobial resistance - 1 Sept 2020
Bitar Ibrahim, Medvecky Matej, Amlerova Jana, Papagiannitsis Costas C, Hrabak Jaroslav
Abstract excerpt
INTRODUCTION: Tuberculosis is considered one of the most fatal diseases worldwide, with an estimation of 10.1 million cases. In this study, whole-genome sequencing was used to determine the genomic characterisation of 40 Mycobacterium tuberculosis isolates from patients with different nationalities hospitalised in the Czech Republic. MATERIALS AND METHODS: Susceptibility testing for first-line drugs was...
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