Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive Immune Profiling of Medullary Thyroid Cancer.

Thyroid : official journal of the American Thyroid Association - 1 Sept 2020

Pozdeyev Nikita, Erickson Timothy A, Zhang Lian, Ellison Kim, Rivard Christopher J, Sams Sharon, Hirsch Fred R, Haugen Bryan R, French Jena D

Abstract excerpt

Background: Despite advances in targeted kinase inhibitor development for patients with medullary thyroid cancer (MTC), most patients develop resistance and would benefit from alternative approaches. Immune-based therapies are now considered for patients with progressive MTC. This study is the first comprehensive assessment of the immune milieu, immune-suppressive molecules, and potential tumor antigens in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcitonin
Share to Carcinoma, Neuroendocrine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune System

Share to Leukocytes

Share to MutS Homolog 2 Protein

Share to Receptors, Virus

Share to RNA-Seq

Share to Thyroiditis, Autoimmune

Source

Open in PubMed Open full text

Identifiers

PMID: 32242507
DOI: 10.1089/thy.2019.0604
PMCID: PMC7869888

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive Immune Profiling of Medullary Thyroid Cancer.PMID 32242507Read ↗

Genomic and Transcriptomic Landscape of RET Wild-Type Medullary Thyroid Cancer and Potential Use of Mitogen-Activated Protein Kinase-Targeted Therapy.Semantic proximity Read ↗

Recent advances in understanding immune phenotypes of thyroid carcinomas: prognostication and emerging therapiesSemantic proximity Read ↗

Immune gene signature delineates a subclass of thyroid cancer with unfavorable clinical outcomes.Semantic proximity Read ↗

Tumor immune microenvironment characteristics of papillary thyroid carcinoma are associated with histopathological aggressiveness and BRAF mutation statusSemantic proximity Read ↗

Molecular intelligence and immune reconnaissance in thyroid cancer: a new paradigm for diagnosis, risk stratification, and therapeutic precision.Semantic proximity Read ↗

Papillary Thyroid Carcinoma with Terminal Immune Exhaustion Phenotype Correlates with Increased Risk of Lymph Node Metastasis: A Combined Flow Cytometry and TCGA Validation StudySemantic proximity Read ↗

RET Alterations Differentiate Molecular Profile of Medullary Thyroid Cancer.Semantic proximity Read ↗

Integrated proteogenomic characterization of medullary thyroid carcinomaSemantic proximity Read ↗

Fundamentals and recent advances in the evaluation and management of medullary thyroid carcinoma.Semantic proximity Read ↗

Multi-omics profiling of papillary thyroid microcarcinoma reveals different somatic mutations and a unique transcriptomic signature.Semantic proximity Read ↗

The Oncocytic Variant of Poorly Differentiated Thyroid Carcinoma Shows a Specific Immune-Related Gene Expression ProfileSemantic proximity Read ↗

Multilayer OMIC Data in Medullary Thyroid Carcinoma Identifies the STAT3 Pathway as a Potential Therapeutic Target in RETM918T Tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.