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Papillary Thyroid Carcinoma with Terminal Immune Exhaustion Phenotype Correlates with Increased Risk of Lymph Node Metastasis: A Combined Flow Cytometry and TCGA Validation Study

2026-07-31

Abstract excerpt

<h4>Background: </h4> Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy, with lymph node metastasis (LNM) being a key predictor of recurrence and poor prognosis. Preoperative detection of LNM remains challenging due to the limitations of imaging modalities, leading to inadequate surgical resection in 20-30% of patients. While immune checkpoint molecules have been implicated in PTC progression...

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Literature Corpus work
097bbe52-a323-5d96-8277-66410297304a
DOI
10.20944/preprints202607.2346.v1
Open publication

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Papillary Thyroid Carcinoma with Terminal Immune Exhaustion Phenotype Correlates with Increased Risk of Lymph Node Metastasis: A Combined Flow Cytometry and TCGA Validation StudyDOI 10.20944/preprints202607.2346.v1
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