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Article

Multi-omics profiling of papillary thyroid microcarcinoma reveals different somatic mutations and a unique transcriptomic signature.

Journal of translational medicine - 20 Mar 2023

Li Qiang, Feng Tienan, Zhu Tengteng, Zhang Weituo, Qian Ying, Zhang Huan, Zheng Xiangqian, Li Dapeng, Yun Xinwei, Zhao Jingzhu, Li Yangyang, Yu Herbert, Gao Ming, Qian Biyun

Abstract excerpt

BACKGROUND: Papillary thyroid microcarcinoma (PTMC) incidence has significantly increased, and some cases still exhibit invasive traits. The entire molecular landscape of PTMC, which can offer hints for the etiology of cancer, is currently absent. METHODS: We compared our findings with those for PTMC in the TCGA by analyzing the largest study at the current stage of whole exome sequencing and RNA-sequencing data...

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Identifiers

PMID: 36941725
DOI: 10.1186/s12967-023-04045-2
PMCID: PMC10026500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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