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Article

Molecular regulation of telomerase activity in aging.

Protein & cell - 1 Sept 2011

Nicholls Craig, Li He, Wang Jian-Qiu, Liu Jun-Ping

Abstract excerpt

The process of aging is mitigated by the maintenance and repair of chromosome ends (telomeres), resulting in extended lifespan. This review examines the molecular mechanisms underlying the actions and regulation of the enzyme telomerase reverse transcriptase (TERT), which functions as the primary mechanism of telomere maintenance and regulates cellular life expectancy. Underpinning increased cell proliferation,...

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Identifiers

PMID: 21976062
DOI: 10.1007/s13238-011-1093-3
PMCID: PMC4875265

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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