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Article

Small ubiquitin-related modifier (SUMO) 3 and SUMO4 gene polymorphisms in Parkinson's disease.

Neurological research - 1 Jun 2020

Küçükali Cem Ismail, Salman Burcu, Yüceer Hande, Ulusoy Canan, Abacı Neslihan, Ekmekci Sema Sırma, Tüzün Erdem, Bilgiç Başar, Hanağası Haşmet Ayhan

Abstract excerpt

Objectives: The ubiquitin/proteasome system is one of the main axes of the pathogenesis of Parkinson's disease (PD). Small ubiquitin-related modifier (SUMO) proteins are involved in many biochemical events including regulation of transcriptional activity, modulation of signal transduction pathways, and response to cellular stress indicating a role for SUMO in the ubiquitin/proteasome system.Methods: In this...

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PMID: 32237992
DOI: 10.1080/01616412.2020.1724464

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