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Genetic Analysis of HSP40/DNAJ Family Genes in Parkinson's Disease: a Large Case-Control Study.

Molecular neurobiology - 1 Sept 2022

Zhang Kailin, Pan Hongxu, Zhao Yuwen, Wang Yige, Zeng Qian, Zhou Xun, He Runcheng, Zhou Xiaoxia, Xiang Yaqin, Zhou Zhou, Li Yu, Xu Qian, Sun Qiying, Tan Jieqiong, Yan Xinxiang, Li Jinchen, Guo Jifeng, Tang Beisha, Liu Zhenhua

Abstract excerpt

Molecular chaperones were reported to play an important role in PD pathogenesis. Recent studies revealed the association of several HSP40/DNAJ family genes with PD, but no genetic analysis of all the DNAJ family genes in PD has been conducted. To systematically analyze the genetic impact of all the DNAJ family genes in PD, we performed genetic analysis for these genes in a large case-control study. We analyzed...

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PMID: 35715682
DOI: 10.1007/s12035-022-02920-5

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