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Article

Evidence for the role of small ubiquitin-like modifier 4 as a general autoimmunity locus in the Japanese population.

The Journal of clinical endocrinology and metabolism - 1 Aug 2006

Tsurumaru Masako, Kawasaki Eiji, Ida Hiroaki, Migita Kiyoshi, Moriuchi Akie, Fukushima Keiko, Fukushima Tetsuya, Abiru Norio, Yamasaki Hironori, Noso Shinsuke, Ikegami Hiroshi, Awata Takuya, Sasaki Hitoshi, Eguchi Katsumi

Abstract excerpt

CONTEXT: Recently, an association of a single nucleotide polymorphism, 163A>G encoding M55V, in the gene SUMO4, which has been shown to be a negative feedback regulator for nuclear factor kappaB, has been reported in type 1 diabetes. OBJECTIVE: To establish whether SUMO4 locus contributes to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16735488
DOI: 10.1210/jc.2006-0206

Genes

SUMO4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16735488-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for the role of small ubiquitin-like modifier 4 as a general autoimmunity locus in the Japanese population.PMID 16735488Read ↗

Association of small ubiquitin-like modifier 4 (SUMO4) variant, located in IDDM5 locus, with type 2 diabetes in the Japanese population.Semantic proximity Read ↗

Polymorphism M55V in gene encoding small ubiquitin-like modifier 4 (SUMO4) protein associates with susceptibility to type 1 (and type 2) diabetes.Semantic proximity Read ↗

Small ubiquitin-like modifier-4 Met55Val polymorphism is associated with glycemic control of Type 2 diabetes mellitus in Taiwan.Semantic proximity Read ↗

Association of SUMO4 M55V polymorphism with susceptibility to autoimmune and inflammatory diseases: a meta-analysis.Semantic proximity Read ↗

Association of SUMO4 M55V polymorphism with autoimmune diabetes in Latvian patients.Semantic proximity Read ↗

Sumoylation Modulates the Susceptibility to Type 1 Diabetes.Semantic proximity Read ↗

Genetic and functional evidence supporting SUMO4 as a type 1 diabetes susceptibility gene.Semantic proximity Read ↗

SUMO4 and its role in type 1 diabetes pathogenesis.Semantic proximity Read ↗

A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes.Semantic proximity Read ↗

SUMO4 163 G>A variation is associated with kidney disease in Indian subjects with type 2 diabetes.Semantic proximity Read ↗

Association of SUMO4 M55V and -94ins/del gene variants with type-2 diabetes.Semantic proximity Read ↗

Association of SUMO4, as a candidate gene for IDDM5, with susceptibility to type 1 diabetes in Asian populations.Semantic proximity Read ↗

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