Article
Genetic sequence changes related to the attenuation of avian infectious bronchitis virus strain TW2575/98.
Virus genes - 1 Jun 2020
Tsai Cheng-Ta, Wu Hung-Yi, Wang Ching-Ho
Abstract excerpt
The attenuated avian infectious bronchitis virus (IBV), derived from a wild strain (TW2575/98w) in chicken embryos after 75 passages, is designed as a commercial vaccine strain (TW2575/98vac) to control the disease in Taiwan. The differences in viral infectivity, replication efficiency, and genome sequences between TW2575/98w and TW2575/98vac were determined and compared. TW2575/98vac caused earlier death of...
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