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Article

Landscape of BRIP1 molecular lesions in gastrointestinal cancers from published genomic studies.

World journal of gastroenterology - 21 Mar 2020

Voutsadakis Ioannis A

Abstract excerpt

BACKGROUND: BRIP1 is a helicase that partners with BRCA1 in the homologous recombination (HR) step in the repair of DNA inter-strand cross-link lesions. It is a rare cause of hereditary ovarian cancer in patients with no mutations of BRCA1 or BRCA2. The role of the protein in other cancers such as gastrointestinal (GI) carcinomas is less well characterized but given its role in DNA repair it could be a candidate...

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Identifiers

PMID: 32231423
DOI: 10.3748/wjg.v26.i11.1197
PMCID: PMC7093310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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