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Article

Mutation of alanine-422 in KaiC leads to a low amplitude of rhythm in the reconstituted cyanobacterial circadian clock.

The Journal of general and applied microbiology - 17 Jun 2020

Nagata Kazuki, Oyama Katsuaki, Ota Atsushi, Azai Chihiro, Terauchi Kazuki

Abstract excerpt

The cyanobacterial circadian oscillator can be reconstituted by mixing the purified clock proteins KaiA, KaiB, and KaiC with ATP in vitro, leading to a 24-h oscillation of KaiC phosphorylation. The cyanobacterial mutant pr1 carrying valine instead of alanine at position 422 of KaiC (KaiC-A422V) lost the ability to shift the phase of the circadian rhythm. In this study, we analyzed KaiC-A422V to investigate the...

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Identifiers

PMID: 32224606
DOI: 10.2323/jgam.2020.01.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutation of alanine-422 in KaiC leads to a low amplitude of rhythm in the reconstituted cyanobacterial circadian clock.PMID 32224606Read ↗

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Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro.Semantic proximity Read ↗

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The roles of the dimeric and tetrameric structures of the clock protein KaiB in the generation of circadian oscillations in cyanobacteria.Semantic proximity Read ↗

ATPase activity of KaiC determines the basic timing for circadian clock of cyanobacteria.Semantic proximity Read ↗

Intramolecular regulation of phosphorylation status of the circadian clock protein KaiC.Semantic proximity Read ↗

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