Article
Association of interleukin-6 circulating levels with coronary artery disease: a meta-analysis implementing mendelian randomization approach.
International journal of cardiology - 31 May 2012
Niu Wenquan, Liu Yan, Qi Yue, Wu Zhijun, Zhu Dingliang, Jin Wei
Abstract excerpt
BACKGROUND: We aim to investigate whether the association between circulating interleukin 6 (IL-6) levels and the risk for coronary artery disease (CAD) is robust and perhaps even causal by a meta-analysis implementing mendelian randomization approach with IL-6 gene G-174C polymorphism as an instrument. METHODS: Data were available from 19 articles encompassing 9417 CAD patients and 15982 controls. A random...
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