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Article

Role of the luxS quorum-sensing system in biofilm formation and virulence of Staphylococcus epidermidis.

Infection and immunity - 1 Jan 2006

Xu Lin, Li Hualin, Vuong Cuong, Vadyvaloo Viveka, Wang Jianping, Yao Yufeng, Otto Michael, Gao Qian

Abstract excerpt

Nosocomial infections caused by Staphylococcus epidermidis are characterized by biofilm formation on implanted medical devices. Quorum-sensing regulation plays a major role in the biofilm development of many bacterial pathogens. Here, we describe luxS, a quorum-sensing system in staphylococci that has a significant impact on biofilm development and virulence. We constructed an isogenic DeltaluxS mutant strain of...

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Identifiers

PMID: 16369005
DOI: 10.1128/IAI.74.1.488-496.2006
PMCID: PMC1346618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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