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Article

Quorum sensing affects biofilm formation through lipopolysaccharide synthesis in Klebsiella pneumoniae.

Research in microbiology - 1 Sept 2010

De Araujo Cécilia, Balestrino Damien, Roth Lucile, Charbonnel Nicolas, Forestier Christiane

Abstract excerpt

Biofilm formation by Klebsiella pneumoniae is modulated by quorum sensing through the synthesis of interspecies AI-2 autoinducers. We characterized in K. pneumoniae the genes homologous to those described in Escherichia coli involved in AI-2 transport, and created two isogenic mutants deleted of lsrCD and tqsA. The levels of extracellular AI-2 with lsrCD and tqsA knockout mutants showed increased and lowered...

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Identifiers

PMID: 20600864
DOI: 10.1016/j.resmic.2010.05.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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