Article
AHR Signaling Dampens Inflammatory Signature in Neonatal Skin γδ T Cells.
International journal of molecular sciences - 24 Mar 2020
Merches Katja, Schiavi Alfonso, Weighardt Heike, Steinwachs Swantje, Teichweyde Nadine, Förster Irmgard, Hochrath Katrin, Schumak Beatrix, Ventura Natascia, Petzsch Patrick, Köhrer Karl, Esser Charlotte
Abstract excerpt
Background Aryl hydrocarbon receptor (AHR)-deficient mice do not support the expansion of dendritic epidermal T cells (DETC), a resident immune cell population in the murine epidermis, which immigrates from the fetal thymus to the skin around birth. Material and Methods In order to identify the gene expression changes underlying the DETC disappearance in AHR-deficient mice, we analyzed microarray RNA-profiles of...
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