Article
Mendel's laws, Mendelian randomization and causal inference in observational data: substantive and nomenclatural issues.
European journal of epidemiology - 1 Feb 2020
Davey Smith George, Holmes Michael V, Davies Neil M, Ebrahim Shah
Abstract excerpt
We respond to criticisms of Mendelian randomization (MR) by Mukamal, Stampfer and Rimm (MSR). MSR consider that MR is receiving too much attention and should be renamed. We explain how MR links to Mendel's laws, the origin of the name and our lack of concern regarding nomenclature. We address MSR's substantive points regarding MR of alcohol and cardiovascular disease, an issue on which they dispute the MR...
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