Article
Near point-of-care, point-mutation test to detect drug resistance in HIV-1: a validation study in a Mexican cohort.
AIDS (London, England) - 15 Jul 2020
Panpradist Nuttada, Beck Ingrid A, Ruth Parker S, Ávila-Ríos Santiago, García-Morales Claudia, Soto-Nava Maribel, Tapia-Trejo Daniela, Matías-Florentino Margarita, Paz-Juarez Hector E, Del Arenal-Sanchez Silvia, Reyes-Terán Gustavo, Lutz Barry R, Frenkel Lisa M
Abstract excerpt
OBJECTIVE: Pretreatment HIV-drug resistance (PDR, HIVDR) to non-nucleoside reverse transcriptase inhibitors (NNRTIs) is increasing globally. NNRTIs continue to be used as first-line antiretroviral therapy (ART) in some communities due to the cost of dolutegravir-based ART or dolutegravir-associated adverse events. A simplified version of the oligonucleotide ligation assay (OLA) - 'OLA-Simple' - is a low-cost,...
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