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Article

Evaluation of the management of pretreatment HIV drug resistance by oligonucleotide ligation assay: a randomised controlled trial.

The lancet. HIV - 1 Feb 2020

Chung Michael H, McGrath Christine J, Beck Ingrid A, Levine Molly, Milne Ross S, So Isaac, Andersen Nina, Dross Sandra, Coombs Robert W, Chohan Bhavna, Yatich Nelly, Kiptinness Catherine, Sakr Samah R, Kiarie James N, Frenkel Lisa M

Abstract excerpt

BACKGROUND: Although experts have recommended testing for pretreatment drug resistance (PDR) before antiretroviral therapy (ART) initiation, there is little evidence to support its implementation. We aimed to establish whether an inexpensive point mutation assay can improve virological suppression by identifying PDR to guide drug selection for ART in a lower-middle income country. METHODS: Investigators did an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31818716
DOI: 10.1016/S2352-3018(19)30337-6
PMCID: PMC6936934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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