Article
Molecular pathogenesis of Coxiella burnetii in a genomics era.
Annals of the New York Academy of Sciences - 1 Jun 2003
Samuel J E, Kiss K, Varghees S
Abstract excerpt
The agent of acute and chronic Q fever, Coxiella burnetii, occupies a unique niche among intracellular pathogens. The mechanisms the organism employs to cause disease are unclear but involve persistence in a parasitophorous vacuole and the subsequent host response. Studies designed to model molecular mechanisms of pathogenesis have relied upon indirect evidence for testing the role of virulence factors since...
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