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Article

The tubal epigenome - An emerging target for ovarian cancer.

Pharmacology & therapeutics - 1 Jun 2020

Reavis Hunter D, Drapkin Ronny

Abstract excerpt

Ovarian cancer is the most lethal gynecologic malignancy in the United States. The mortality of this disease is primarily attributed to challenges in early detection and therapeutic resistance. Recent studies indicate that the majority of high-grade serous ovarian carcinomas (HGSCs) originate from aberrant fallopian tube epithelial (FTE) cells. This shift in thinking about ovarian cancer pathogenesis has been met...

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Share to Carcinoma, Ovarian Epithelial
Share to Epigenesis, Genetic
Share to Epigenome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Fallopian Tubes

Share to Neoplasms, Cystic, Mucinous, and Serous

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Source

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Identifiers

PMID: 32197795
DOI: 10.1016/j.pharmthera.2020.107524
PMCID: PMC7237289

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