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Article

Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma.

Oncotarget - 5 Jul 2016

de Cristofaro Tiziana, Di Palma Tina, Soriano Amata Amy, Monticelli Antonella, Affinito Ornella, Cocozza Sergio, Zannini Mariastella

Abstract excerpt

Understanding the biology and molecular pathogenesis of ovarian epithelial cancer (EOC) is key to developing improved diagnostic and prognostic indicators and effective therapies. Although research has traditionally focused on the hypothesis that high-grade serous carcinoma (HGSC) arises from the ovarian surface epithelium (OSE), recent studies suggest that additional sites of origin exist and a substantial...

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Share to Cystadenocarcinoma, Serous
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27259239
DOI: 10.18632/oncotarget.9740
PMCID: PMC5173106

Genes

PAX8

Provenance

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